ImmunoSpot® Analyzers
In 1995, CTL’s founding scientists pioneered image analysis-based ELISPOT counting (US Patent 6,410,252 B1), laying the foundation for the development of ImmunoSpot® Analyzers. Since then, thousands of these instruments have been sold globally, supporting the advanced imaging needs of leading academic and biotechnology researchers. Discover why ImmunoSpot® Analyzers continue to set the benchmark in the field.
Not only are ImmunoSpot® Analyzers the most widely adopted ELISPOT/FluoroSpot analyzers on the market, they are also highly versatile. These systems can be used to read a variety of microtiter plate- or Peri-dish-based assays under both visible and fluorescent light, across microscopic and macroscopic ranges. Powered by BioSpot™ software, their capabilities include cell counting, cytotoxicity and serum neutralization assays, colony counting, and more — delivering the functionality of multiple instruments in one compact system.
Explore how CTL’s Readers have earned their reputation as the gold standard for viral infectivity assays.
CTL offers an extensive selection of Reader models to suit various needs and budgets. Browse our latest model lines below. Our team is happy to help you choose the model that’s right for you. We also provide factory refurbished analyzers and analysis services.
Fluorescence Readers — Precision in Every Signal
Advanced multi-color detection systems designed for high-sensitivity FluoroSpot analysis and single-cell resolution assays.
Features & Specifications
Visible Light Readers — Clarity You Can Count On
Reliable readers for ELISPOT and colony assays, delivering accurate visible-light imaging for immune monitoring and research workflows.
Features & Specifications
| Distinguishing Features | S6 Lite M2 | S6 Entry M2 | S6 Macro M2 | S6 Micro M2 |
| Optical Zoom Capability | (✓) | (✓) | ✓ | ✓ |
| Well Formats | 96 Strip plate in 96 well format |
96, 384, 1536 Strip plate in 96 well format |
6, 12, 24, 48, 96 Strip plate in 96 well format (upgradable to all Petri dish formats) |
24, 48, 96, 384, 1536 Terasaki Strip plate in 96 well format (upgradeable to rapid 6/Petri) |
| Top / Bottom Light | ✓ / ✕ | ✓ / ✓ | ✓ / ✓ | ✓ / ✓ |
| High-througput (Stacker/Robot compatibility) | ✕ | ✓ | ✓ | ✓ |
| Integrated Barcode Reader | ✕ | ✓ | ✓ | ✓ |
| ELISPOT Applications | ||||
| Single color ELISPOT | ✓ | ✓ | ✓ | ✓ |
| Double color ELISPOT | ✓ | ✓ | ✓ | ✓ |
| Non-ELISPOT Immunological Applications |
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| ELISA | ✕ | ✓ | ✓ | ✓ |
| BioSpot™ | ✕ | ✓ | ✓ | ✓ |
| T Cell Proliferation Assays | ✓ | ✓ | ✓ | ✓ |
| Nucleic Acid and Protein Quantification | ✕ | ✓ | ✓ | ✓ |
| Histology Slide Analysis Capability | ✕ | ✕ | ✕ | ✓ |
| Microscopic Imaging | ✕ | ✕ | ✕ | ✓ |
| Visible Light Array Analysis | ✕ | ✕ | ✓ | ✓ |
| Advanced Features | ||||
| BSL 3/4 Suitability | ✕ | ✓ | ✓ | ✓ |
| Space Saving Design | ✓ | ✓ | ✓ | ✓ |
| Max Image Resolution / Well (megapixels) | 1.2 | 5 | 10 | 25 |
| Regulatory Compliance | ✕ | Tiered Solutions | Tiered Solutions | Tiered Solutions |
| Software Suites | ||||
| ImmunoSpot® Single-Color ELISPOT Enzymatic | Renewable Software License | ✓ | ✓ | ✓ |
| ImmunoSpot® Double-Color ELISPOT Enzymatic | ✕ (upgradeable) | ✓ | ✓ | ✓ |
| BioSpot™ | ✕ | ✓ | ✓ | ✓ |
| ODense™ | ✕ | ✓ | ✓ | ✓ |
| SpotMap® | ✕ (upgradeable) | ✓ | ✓ | ✓ |
| Image Annotator | ✕ (upgradeable) | ✓ | ✓ | ✓ |
| SpotStat™ | ✕ (upgradeable) | ✓ | ✓ | ✓ |
| ReagentTracker™ | ✕ | ✓ | ✓ | ✓ |
| ExpressQualify™ | ✕ | ✓ | ✓ | ✓ |
| ImmunoQualify™ | ✕ | ✕ (upgradeable) | ✕ (upgradeable) | ✕ (upgradeable) |
| ImmunoCompliance™ Suite | ✕ | ✕ (upgradeable) | ✕ (upgradeable) | ✕ (upgradeable) |
