Are You Using the Right Readout System for Your Immunology Research?

CTL’s unmatched strength lies in its high-throughput T cell monitoring expertise and global leadership in ELISPOT (Enzyme-Linked ImmunoSpot® Assay) technology. With decades of experience in contract research, numerous pharmaceutical and biotechnology companies trust us to evaluate immune responses to their vaccines, drugs, and biological products using the ELISPOT technique.

---

The ability to measure T cell responses to antigens is critical for basic research, drug discovery, and the management of various diseases. ELISPOT testing is especially valuable when detecting low-frequency T cell responses is needed for ex vivo immune readouts. Single-cell resolution T cell analysis is essential for advancing research and treatment of allergies, autoimmunity, understanding transplant rejection or acceptance, enhancing drug and vaccine development, and monitoring cancer therapies.

The ELISPOT technique enables researchers to capture secretory footprints as colored spots within 96-well plates, which are then scanned, counted, and statistically analyzed. This method not only helps determine the positive or negative immune response of patient groups to a vaccine, drug, or biological product, but also quantifies the individual’s immune response strength.

---

The ELISPOT Method Unlocks Opportunities for:

• Single-cell T cell immunity testing in pre-clinical and clinical samples

• Determinant mapping with overlapping peptides

• Cytotoxic T cell response measurement

• B cell response measurement

• Running multiple assays with limited sample material

• High-throughput testing (~150 specimens/day, ~450 specimens/week)

---

With extensive experience in assay optimization, qualification, and validation across multiple species — including human, monkey, mouse, rat, rabbit, and pig — CTL delivers comprehensive support for diverse immunological testing needs.

For further information or a quote, please contact us today.