ImmunoSpot® Analyzers

In 1995, CTL’s founding scientists pioneered image analysis-based ELISPOT counting (US Patent 6,410,252 B1), laying the foundation for the development of ImmunoSpot® Analyzers. Since then, thousands of these instruments have been sold globally, supporting the advanced imaging needs of leading academic and biotechnology researchers. Discover why ImmunoSpot® Analyzers continue to set the benchmark in the field.

Not only are ImmunoSpot® Analyzers the most widely adopted ELISPOT/FluoroSpot analyzers on the market, they are also highly versatile. These systems can be used to read a variety of microtiter plate- or Peri-dish-based assays under both visible and fluorescent light, across microscopic and macroscopic ranges. Powered by BioSpot™ software, their capabilities include cell counting, cytotoxicity and serum neutralization assays, colony counting, and more — delivering the functionality of multiple instruments in one compact system.

Explore how CTL’s Readers have earned their reputation as the gold standard for viral infectivity assays.

CTL offers an extensive selection of Reader models to suit various needs and budgets. Browse our latest model lines below. Our team is happy to help you choose the model that’s right for you. We also provide factory refurbished analyzers and analysis services.

Fluorescence Readers — Precision in Every Signal

Advanced multi-color detection systems designed for high-sensitivity FluoroSpot analysis and single-cell resolution assays.

Features & Specifications

S6 FluoroCore M2

S6 UltraM2

S6 Flex M2

S6 Universal M2

S6 Ultimate M2

Visible Light Readers — Clarity You Can Count On

Reliable readers for ELISPOT and colony assays, delivering accurate visible-light imaging for immune monitoring and research workflows.

Features & Specifications

S6 Lite M2

S6 Entry M2

S6 Flex M2

S6 Macro M2

S6 Micro M2

Distinguishing Features S6 Lite M2 S6 Entry M2 S6 Macro M2 S6 Micro M2
Optical Zoom Capability (✓) (✓)
Well Formats 96
Strip plate in 96 well format
96, 384, 1536
Strip plate in 96 well format
6, 12, 24, 48, 96
Strip plate in 96 well format
(upgradable to all Petri dish formats)
24, 48, 96, 384, 1536 Terasaki
Strip plate in 96 well format
(upgradeable to rapid 6/Petri)
Top / Bottom Light ✓ / ✕ ✓ / ✓ ✓ / ✓ ✓ / ✓
High-througput (Stacker/Robot compatibility)
Integrated Barcode Reader
ELISPOT Applications        
Single color ELISPOT
Double color ELISPOT
Non-ELISPOT
Immunological
Applications
       
ELISA
BioSpot™
T Cell Proliferation Assays
Nucleic Acid and Protein Quantification
Histology Slide Analysis Capability
Microscopic Imaging
Visible Light Array Analysis
Advanced Features        
BSL 3/4 Suitability
Space Saving Design
Max Image Resolution / Well (megapixels) 1.2 5 10 25
Regulatory Compliance Tiered Solutions Tiered Solutions Tiered Solutions
Software Suites        
ImmunoSpot® Single-Color ELISPOT Enzymatic Renewable Software License
ImmunoSpot® Double-Color ELISPOT Enzymatic ✕ (upgradeable)
BioSpot™
ODense™
SpotMap® ✕ (upgradeable)
Image Annotator ✕ (upgradeable)
SpotStat™ ✕ (upgradeable)
ReagentTracker™
ExpressQualify™
ImmunoQualify™ ✕ (upgradeable) ✕ (upgradeable) ✕ (upgradeable)
ImmunoCompliance™ Suite ✕ (upgradeable) ✕ (upgradeable) ✕ (upgradeable)